Selected publications

• van Os W, Nussbaumer-Pröll A, Pham AD, Wijnant GJ, Ngougni Pokem P, Van Bambeke F, van Hasselt JGC, Zeitlinger M. Pharmacokinetic/pharmacodynamic model-based optimization of temocillin dosing strategies for the treatment of systemic infections. J Antimicrob Chemother. 2024 Oct 1;79(10):2484-2492.

• Sanz-Codina M, van Os W, Pham AD, Jorda A, Wölf-Duchek M, Bergmann F, Lackner E, Lier C, van Hasselt JGC, Minichmayr IK, Dorn C, Zeitlinger M, Al Jalali V. Target-site cefiderocol pharmacokinetics in soft tissues of healthy volunteers. J Antimicrob Chemother. 2024 Dec 2;79(12):3281-3288.

• Mekking XM, Velthoven-Graafland K, Teulen MJA, Brüggemann RJM, Te Brake LHM, Jager NGL. Development and validation of an UPLC-MS/MS assay for the simultaneous quantification of seven commonly used antibiotics in human plasma and its application in therapeutic drug monitoring. J Antimicrob Chemother. 2024 Apr 2;79(4):883-890.

• Jansen AME, Mertens B, Spriet I, Verweij PE, Schouten J, Wauters J, Debaveye Y, Ter Heine R, Brüggemann RJM. Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies. Clin Pharmacokinet. 2023 Dec;62(12):1701-1711.

• van Groesen E, Mons E, Kotsogianni I, Arts M, Tehrani KHME, Wade N, Lysenko V, Stel FM, Zwerus JT, De Benedetti S, Bakker A, Chakraborty P, van der Stelt M, Scheffers DJ, Gooskens J, Smits WK, Holden K, Gilmour PS, Willemse J, Hitchcock CA, van Hasselt JGC, Schneider T, Martin NI. Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Sci Transl Med. 2024 Aug 7;16(759):eabo4736.

• Mehta K, Guo T, van der Graaf PH, van Hasselt JGC. Model-based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug-resistant tuberculosis. Br J Clin Pharmacol. 2024 Feb;90(2):463-474.